Vayne Build

The best Vayne item build Season 12 starts with a Doran's Shield and purchase. The Best mythic item for Vayne you will build is Gargoyle Stoneplate Dead Man's Plate Zeke's Convergence Death's Dance Mortal Reminder Lord Dominik's Regards Rapid Firecannon Duskblade of Draktharr Redemption Edge of Night Knight's Vow Trinity Force Zhonya's Hourglass Locket of the Iron Solari Manamune Rabadon's Deathcap Rod of Ages Void Staff Spirit Visage Frozen Heart Phantom Dancer Youmuu's Ghostblade Randuin's Omen Ionian Boots of Lucidity Morellonomicon Maw of Malmortius Blade of the Ruined King Seraph's Embrace Ravenous Hydra Runaan's Hurricane Muramana Mercurial Scimitar Essence Reaver Ardent Censer Thornmail Stormrazor Guinsoo's Rageblade Archangel's Staff Banshee's Veil Berserker's Greaves Boots of Swiftness Wit's End Warmog's Armor Guardian Angel Black Cleaver Mejai's Soulstealer Sorcerer's Shoes Mercury's Treads Nashor's Tooth Rylai's Crystal Scepter Bloodthirster Sanguine Blade Umbral Glaive Infinity Edge Titanic Hydra Sterak's Gage Lich Bane Abyssal Mask Shard of True Ice Bulwark of the Mountain Black Mist Scythe Pauldrons of Whiterock Staff of Flowing Water Mobility Boots Force of Nature Plated Steelcaps Chempunk Chainsword Chemtech Putrifier Cosmic Drive Demonic Embrace Divine Sunderer Eclipse Everfrost Frostfire Gauntlet Galeforce Goredrinker Hextech Rocketbelt Horizon Focus Immortal Shieldbow Imperial Mandate Kraken Slayer Liandry's Anguish Luden's Tempest Mikael's Blessing Moonstone Renewer Navori Quickblades Night Harvester Prowler's Claw Riftmaker Serpent's Fang Serylda's Grudge Shurelya's Battlesong Stridebreaker Sunfire Aegis The Collector Turbo Chemtank Needlessly Large Rod Stopwatch Pickaxe B. F. Sword Ruby Crystal Null-Magic Mantle Rejuvenation Bead Cloth Armor Long Sword Dagger Amplifying Tome Sapphire Crystal Faerie Charm Rejuvenation Bead Cloak of Agility Dark Seal Steel Shoulderguards Spectral Sickle Spellthief's Edge Relic Shield Boots Tear of the Goddess Sheen Bramble Vest Lost Chapter Caulfield's Warhammer Serrated Dirk Kircheis Shard Aether Wisp Bami's Cinder Crystalline Bracer Forbidden Idol Hexdrinker Kindlegem Quicksilver Sash Seeker's Armguard Spectre's Cowl Oblivion Orb Recurve Bow Chain Vest Aegis of the Legion Executioner's Calling Warden's Mail Fiendish Codex Negatron Cloak Phage Giant's Belt Zeal Tiamat Last Whisper Frostfang Targon's Buckler Blighting Jewel Glacial Buckler Doran's Shield Doran's Ring Doran's Blade Cull Vampiric Scepter followed by a Gargoyle Stoneplate Dead Man's Plate Zeke's Convergence Death's Dance Mortal Reminder Lord Dominik's Regards Rapid Firecannon Duskblade of Draktharr Redemption Edge of Night Knight's Vow Trinity Force Zhonya's Hourglass Locket of the Iron Solari Manamune Rabadon's Deathcap Rod of Ages Void Staff Spirit Visage Frozen Heart Phantom Dancer Youmuu's Ghostblade Randuin's Omen Ionian Boots of Lucidity Morellonomicon Maw of Malmortius Blade of the Ruined King Seraph's Embrace Ravenous Hydra Runaan's Hurricane Muramana Mercurial Scimitar Essence Reaver Ardent Censer Thornmail Stormrazor Guinsoo's Rageblade Archangel's Staff Banshee's Veil Berserker's Greaves Boots of Swiftness Wit's End Warmog's Armor Guardian Angel Black Cleaver Mejai's Soulstealer Sorcerer's Shoes Mercury's Treads Nashor's Tooth Rylai's Crystal Scepter Bloodthirster Sanguine Blade Umbral Glaive Infinity Edge Titanic Hydra Sterak's Gage Lich Bane Abyssal Mask Shard of True Ice Bulwark of the Mountain Black Mist Scythe Pauldrons of Whiterock Staff of Flowing Water Mobility Boots Force of Nature Plated Steelcaps Chempunk Chainsword Chemtech Putrifier Cosmic Drive Demonic Embrace Divine Sunderer Eclipse Everfrost Frostfire Gauntlet Galeforce Goredrinker Hextech Rocketbelt Horizon Focus Immortal Shieldbow Imperial Mandate Kraken Slayer Liandry's Anguish Luden's Tempest Mikael's Blessing Moonstone Renewer Navori Quickblades Night Harvester Prowler's Claw Riftmaker Serpent's Fang Serylda's Grudge Shurelya's Battlesong Stridebreaker Sunfire Aegis The Collector Turbo Chemtank Needlessly Large Rod Stopwatch Pickaxe B. F. Sword Ruby Crystal Null-Magic Mantle Rejuvenation Bead Cloth Armor Long Sword Dagger Amplifying Tome Sapphire Crystal Faerie Charm Rejuvenation Bead Cloak of Agility Dark Seal Steel Shoulderguards Spectral Sickle Spellthief's Edge Relic Shield Boots Tear of the Goddess Sheen Bramble Vest Lost Chapter Caulfield's Warhammer Serrated Dirk Kircheis Shard Aether Wisp Bami's Cinder Crystalline Bracer Forbidden Idol Hexdrinker Kindlegem Quicksilver Sash Seeker's Armguard Spectre's Cowl Oblivion Orb Recurve Bow Chain Vest Aegis of the Legion Executioner's Calling Warden's Mail Fiendish Codex Negatron Cloak Phage Giant's Belt Zeal Tiamat Last Whisper Frostfang Targon's Buckler Blighting Jewel Glacial Buckler Doran's Shield Doran's Ring Doran's Blade Cull Vampiric Scepter purchase. The final items you will need to complete your champion item build guide are a Gargoyle Stoneplate Dead Man's Plate Zeke's Convergence Death's Dance Mortal Reminder Lord Dominik's Regards Rapid Firecannon Duskblade of Draktharr Redemption Edge of Night Knight's Vow Trinity Force Zhonya's Hourglass Locket of the Iron Solari Manamune Rabadon's Deathcap Rod of Ages Void Staff Spirit Visage Frozen Heart Phantom Dancer Youmuu's Ghostblade Randuin's Omen Ionian Boots of Lucidity Morellonomicon Maw of Malmortius Blade of the Ruined King Seraph's Embrace Ravenous Hydra Runaan's Hurricane Muramana Mercurial Scimitar Essence Reaver Ardent Censer Thornmail Stormrazor Guinsoo's Rageblade Archangel's Staff Banshee's Veil Berserker's Greaves Boots of Swiftness Wit's End Warmog's Armor Guardian Angel Black Cleaver Mejai's Soulstealer Sorcerer's Shoes Mercury's Treads Nashor's Tooth Rylai's Crystal Scepter Bloodthirster Sanguine Blade Umbral Glaive Infinity Edge Titanic Hydra Sterak's Gage Lich Bane Abyssal Mask Shard of True Ice Bulwark of the Mountain Black Mist Scythe Pauldrons of Whiterock Staff of Flowing Water Mobility Boots Force of Nature Plated Steelcaps Chempunk Chainsword Chemtech Putrifier Cosmic Drive Demonic Embrace Divine Sunderer Eclipse Everfrost Frostfire Gauntlet Galeforce Goredrinker Hextech Rocketbelt Horizon Focus Immortal Shieldbow Imperial Mandate Kraken Slayer Liandry's Anguish Luden's Tempest Mikael's Blessing Moonstone Renewer Navori Quickblades Night Harvester Prowler's Claw Riftmaker Serpent's Fang Serylda's Grudge Shurelya's Battlesong Stridebreaker Sunfire Aegis The Collector Turbo Chemtank Needlessly Large Rod Stopwatch Pickaxe B. F. Sword Ruby Crystal Null-Magic Mantle Rejuvenation Bead Cloth Armor Long Sword Dagger Amplifying Tome Sapphire Crystal Faerie Charm Rejuvenation Bead Cloak of Agility Dark Seal Steel Shoulderguards Spectral Sickle Spellthief's Edge Relic Shield Boots Tear of the Goddess Sheen Bramble Vest Lost Chapter Caulfield's Warhammer Serrated Dirk Kircheis Shard Aether Wisp Bami's Cinder Crystalline Bracer Forbidden Idol Hexdrinker Kindlegem Quicksilver Sash Seeker's Armguard Spectre's Cowl Oblivion Orb Recurve Bow Chain Vest Aegis of the Legion Executioner's Calling Warden's Mail Fiendish Codex Negatron Cloak Phage Giant's Belt Zeal Tiamat Last Whisper Frostfang Targon's Buckler Blighting Jewel Glacial Buckler Doran's Shield Doran's Ring Doran's Blade Cull Vampiric Scepter and or Gargoyle Stoneplate Dead Man's Plate Zeke's Convergence Death's Dance Mortal Reminder Lord Dominik's Regards Rapid Firecannon Duskblade of Draktharr Redemption Edge of Night Knight's Vow Trinity Force Zhonya's Hourglass Locket of the Iron Solari Manamune Rabadon's Deathcap Rod of Ages Void Staff Spirit Visage Frozen Heart Phantom Dancer Youmuu's Ghostblade Randuin's Omen Ionian Boots of Lucidity Morellonomicon Maw of Malmortius Blade of the Ruined King Seraph's Embrace Ravenous Hydra Runaan's Hurricane Muramana Mercurial Scimitar Essence Reaver Ardent Censer Thornmail Stormrazor Guinsoo's Rageblade Archangel's Staff Banshee's Veil Berserker's Greaves Boots of Swiftness Wit's End Warmog's Armor Guardian Angel Black Cleaver Mejai's Soulstealer Sorcerer's Shoes Mercury's Treads Nashor's Tooth Rylai's Crystal Scepter Bloodthirster Sanguine Blade Umbral Glaive Infinity Edge Titanic Hydra Sterak's Gage Lich Bane Abyssal Mask Shard of True Ice Bulwark of the Mountain Black Mist Scythe Pauldrons of Whiterock Staff of Flowing Water Mobility Boots Force of Nature Plated Steelcaps Chempunk Chainsword Chemtech Putrifier Cosmic Drive Demonic Embrace Divine Sunderer Eclipse Everfrost Frostfire Gauntlet Galeforce Goredrinker Hextech Rocketbelt Horizon Focus Immortal Shieldbow Imperial Mandate Kraken Slayer Liandry's Anguish Luden's Tempest Mikael's Blessing Moonstone Renewer Navori Quickblades Night Harvester Prowler's Claw Riftmaker Serpent's Fang Serylda's Grudge Shurelya's Battlesong Stridebreaker Sunfire Aegis The Collector Turbo Chemtank Needlessly Large Rod Stopwatch Pickaxe B. F. Sword Ruby Crystal Null-Magic Mantle Rejuvenation Bead Cloth Armor Long Sword Dagger Amplifying Tome Sapphire Crystal Faerie Charm Rejuvenation Bead Cloak of Agility Dark Seal Steel Shoulderguards Spectral Sickle Spellthief's Edge Relic Shield Boots Tear of the Goddess Sheen Bramble Vest Lost Chapter Caulfield's Warhammer Serrated Dirk Kircheis Shard Aether Wisp Bami's Cinder Crystalline Bracer Forbidden Idol Hexdrinker Kindlegem Quicksilver Sash Seeker's Armguard Spectre's Cowl Oblivion Orb Recurve Bow Chain Vest Aegis of the Legion Executioner's Calling Warden's Mail Fiendish Codex Negatron Cloak Phage Giant's Belt Zeal Tiamat Last Whisper Frostfang Targon's Buckler Blighting Jewel Glacial Buckler Doran's Shield Doran's Ring Doran's Blade Cull Vampiric Scepter. Make sure to use Flash and Heal as your summoner spells.

1. Gargoyle StoneplateDead Man's PlateZeke's ConvergenceDeath's DanceMortal ReminderLord Dominik's RegardsRapid FirecannonDuskblade of DraktharrRedemptionEdge of NightKnight's VowTrinity ForceZhonya's HourglassLocket of the Iron SolariManamuneRabadon's DeathcapRod of AgesVoid StaffSpirit VisageFrozen HeartPhantom DancerYoumuu's GhostbladeRanduin's OmenIonian Boots of LucidityMorellonomiconMaw of MalmortiusBlade of the Ruined KingSeraph's EmbraceRavenous HydraRunaan's HurricaneMuramanaMercurial ScimitarEssence ReaverArdent CenserThornmailStormrazorGuinsoo's RagebladeArchangel's StaffBanshee's VeilBerserker's GreavesBoots of SwiftnessWit's EndWarmog's ArmorGuardian AngelBlack CleaverMejai's SoulstealerSorcerer's ShoesMercury's TreadsNashor's ToothRylai's Crystal ScepterBloodthirsterSanguine BladeUmbral GlaiveInfinity EdgeTitanic HydraSterak's GageLich BaneAbyssal MaskShard of True IceBulwark of the MountainBlack Mist ScythePauldrons of WhiterockStaff of Flowing WaterMobility BootsForce of NaturePlated SteelcapsChempunk ChainswordChemtech PutrifierCosmic DriveDemonic EmbraceDivine SundererEclipseEverfrostFrostfire GauntletGaleforceGoredrinkerHextech RocketbeltHorizon FocusImmortal ShieldbowImperial MandateKraken SlayerLiandry's AnguishLuden's TempestMikael's BlessingMoonstone RenewerNavori QuickbladesNight HarvesterProwler's ClawRiftmakerSerpent's FangSerylda's GrudgeShurelya's BattlesongStridebreakerSunfire AegisThe CollectorTurbo ChemtankNeedlessly Large RodStopwatchPickaxeB. F. SwordRuby CrystalNull-Magic MantleRejuvenation BeadCloth ArmorLong SwordDaggerAmplifying TomeSapphire CrystalFaerie CharmRejuvenation BeadCloak of AgilityDark SealSteel ShoulderguardsSpectral SickleSpellthief's EdgeRelic ShieldBootsTear of the GoddessSheenBramble VestLost ChapterCaulfield's WarhammerSerrated DirkKircheis ShardAether WispBami's CinderCrystalline BracerForbidden IdolHexdrinkerKindlegemQuicksilver SashSeeker's ArmguardSpectre's CowlOblivion OrbRecurve BowChain VestAegis of the LegionExecutioner's CallingWarden's MailFiendish CodexNegatron CloakPhage Giant's BeltZealTiamatLast WhisperFrostfangTargon's BucklerBlighting JewelGlacial BucklerDoran's ShieldDoran's RingDoran's BladeCullVampiric Scepter
2. Gargoyle StoneplateDead Man's PlateZeke's ConvergenceDeath's DanceMortal ReminderLord Dominik's RegardsRapid FirecannonDuskblade of DraktharrRedemptionEdge of NightKnight's VowTrinity ForceZhonya's HourglassLocket of the Iron SolariManamuneRabadon's DeathcapRod of AgesVoid StaffSpirit VisageFrozen HeartPhantom DancerYoumuu's GhostbladeRanduin's OmenIonian Boots of LucidityMorellonomiconMaw of MalmortiusBlade of the Ruined KingSeraph's EmbraceRavenous HydraRunaan's HurricaneMuramanaMercurial ScimitarEssence ReaverArdent CenserThornmailStormrazorGuinsoo's RagebladeArchangel's StaffBanshee's VeilBerserker's GreavesBoots of SwiftnessWit's EndWarmog's ArmorGuardian AngelBlack CleaverMejai's SoulstealerSorcerer's ShoesMercury's TreadsNashor's ToothRylai's Crystal ScepterBloodthirsterSanguine BladeUmbral GlaiveInfinity EdgeTitanic HydraSterak's GageLich BaneAbyssal MaskShard of True IceBulwark of the MountainBlack Mist ScythePauldrons of WhiterockStaff of Flowing WaterMobility BootsForce of NaturePlated SteelcapsChempunk ChainswordChemtech PutrifierCosmic DriveDemonic EmbraceDivine SundererEclipseEverfrostFrostfire GauntletGaleforceGoredrinkerHextech RocketbeltHorizon FocusImmortal ShieldbowImperial MandateKraken SlayerLiandry's AnguishLuden's TempestMikael's BlessingMoonstone RenewerNavori QuickbladesNight HarvesterProwler's ClawRiftmakerSerpent's FangSerylda's GrudgeShurelya's BattlesongStridebreakerSunfire AegisThe CollectorTurbo ChemtankNeedlessly Large RodStopwatchPickaxeB. F. SwordRuby CrystalNull-Magic MantleRejuvenation BeadCloth ArmorLong SwordDaggerAmplifying TomeSapphire CrystalFaerie CharmRejuvenation BeadCloak of AgilityDark SealSteel ShoulderguardsSpectral SickleSpellthief's EdgeRelic ShieldBootsTear of the GoddessSheenBramble VestLost ChapterCaulfield's WarhammerSerrated DirkKircheis ShardAether WispBami's CinderCrystalline BracerForbidden IdolHexdrinkerKindlegemQuicksilver SashSeeker's ArmguardSpectre's CowlOblivion OrbRecurve BowChain VestAegis of the LegionExecutioner's CallingWarden's MailFiendish CodexNegatron CloakPhage Giant's BeltZealTiamatLast WhisperFrostfangTargon's BucklerBlighting JewelGlacial BucklerDoran's ShieldDoran's RingDoran's BladeCullVampiric Scepter
3. Gargoyle StoneplateDead Man's PlateZeke's ConvergenceDeath's DanceMortal ReminderLord Dominik's RegardsRapid FirecannonDuskblade of DraktharrRedemptionEdge of NightKnight's VowTrinity ForceZhonya's HourglassLocket of the Iron SolariManamuneRabadon's DeathcapRod of AgesVoid StaffSpirit VisageFrozen HeartPhantom DancerYoumuu's GhostbladeRanduin's OmenIonian Boots of LucidityMorellonomiconMaw of MalmortiusBlade of the Ruined KingSeraph's EmbraceRavenous HydraRunaan's HurricaneMuramanaMercurial ScimitarEssence ReaverArdent CenserThornmailStormrazorGuinsoo's RagebladeArchangel's StaffBanshee's VeilBerserker's GreavesBoots of SwiftnessWit's EndWarmog's ArmorGuardian AngelBlack CleaverMejai's SoulstealerSorcerer's ShoesMercury's TreadsNashor's ToothRylai's Crystal ScepterBloodthirsterSanguine BladeUmbral GlaiveInfinity EdgeTitanic HydraSterak's GageLich BaneAbyssal MaskShard of True IceBulwark of the MountainBlack Mist ScythePauldrons of WhiterockStaff of Flowing WaterMobility BootsForce of NaturePlated SteelcapsChempunk ChainswordChemtech PutrifierCosmic DriveDemonic EmbraceDivine SundererEclipseEverfrostFrostfire GauntletGaleforceGoredrinkerHextech RocketbeltHorizon FocusImmortal ShieldbowImperial MandateKraken SlayerLiandry's AnguishLuden's TempestMikael's BlessingMoonstone RenewerNavori QuickbladesNight HarvesterProwler's ClawRiftmakerSerpent's FangSerylda's GrudgeShurelya's BattlesongStridebreakerSunfire AegisThe CollectorTurbo ChemtankNeedlessly Large RodStopwatchPickaxeB. F. SwordRuby CrystalNull-Magic MantleRejuvenation BeadCloth ArmorLong SwordDaggerAmplifying TomeSapphire CrystalFaerie CharmRejuvenation BeadCloak of AgilityDark SealSteel ShoulderguardsSpectral SickleSpellthief's EdgeRelic ShieldBootsTear of the GoddessSheenBramble VestLost ChapterCaulfield's WarhammerSerrated DirkKircheis ShardAether WispBami's CinderCrystalline BracerForbidden IdolHexdrinkerKindlegemQuicksilver SashSeeker's ArmguardSpectre's CowlOblivion OrbRecurve BowChain VestAegis of the LegionExecutioner's CallingWarden's MailFiendish CodexNegatron CloakPhage Giant's BeltZealTiamatLast WhisperFrostfangTargon's BucklerBlighting JewelGlacial BucklerDoran's ShieldDoran's RingDoran's BladeCullVampiric Scepter
4. Gargoyle StoneplateDead Man's PlateZeke's ConvergenceDeath's DanceMortal ReminderLord Dominik's RegardsRapid FirecannonDuskblade of DraktharrRedemptionEdge of NightKnight's VowTrinity ForceZhonya's HourglassLocket of the Iron SolariManamuneRabadon's DeathcapRod of AgesVoid StaffSpirit VisageFrozen HeartPhantom DancerYoumuu's GhostbladeRanduin's OmenIonian Boots of LucidityMorellonomiconMaw of MalmortiusBlade of the Ruined KingSeraph's EmbraceRavenous HydraRunaan's HurricaneMuramanaMercurial ScimitarEssence ReaverArdent CenserThornmailStormrazorGuinsoo's RagebladeArchangel's StaffBanshee's VeilBerserker's GreavesBoots of SwiftnessWit's EndWarmog's ArmorGuardian AngelBlack CleaverMejai's SoulstealerSorcerer's ShoesMercury's TreadsNashor's ToothRylai's Crystal ScepterBloodthirsterSanguine BladeUmbral GlaiveInfinity EdgeTitanic HydraSterak's GageLich BaneAbyssal MaskShard of True IceBulwark of the MountainBlack Mist ScythePauldrons of WhiterockStaff of Flowing WaterMobility BootsForce of NaturePlated SteelcapsChempunk ChainswordChemtech PutrifierCosmic DriveDemonic EmbraceDivine SundererEclipseEverfrostFrostfire GauntletGaleforceGoredrinkerHextech RocketbeltHorizon FocusImmortal ShieldbowImperial MandateKraken SlayerLiandry's AnguishLuden's TempestMikael's BlessingMoonstone RenewerNavori QuickbladesNight HarvesterProwler's ClawRiftmakerSerpent's FangSerylda's GrudgeShurelya's BattlesongStridebreakerSunfire AegisThe CollectorTurbo ChemtankNeedlessly Large RodStopwatchPickaxeB. F. SwordRuby CrystalNull-Magic MantleRejuvenation BeadCloth ArmorLong SwordDaggerAmplifying TomeSapphire CrystalFaerie CharmRejuvenation BeadCloak of AgilityDark SealSteel ShoulderguardsSpectral SickleSpellthief's EdgeRelic ShieldBootsTear of the GoddessSheenBramble VestLost ChapterCaulfield's WarhammerSerrated DirkKircheis ShardAether WispBami's CinderCrystalline BracerForbidden IdolHexdrinkerKindlegemQuicksilver SashSeeker's ArmguardSpectre's CowlOblivion OrbRecurve BowChain VestAegis of the LegionExecutioner's CallingWarden's MailFiendish CodexNegatron CloakPhage Giant's BeltZealTiamatLast WhisperFrostfangTargon's BucklerBlighting JewelGlacial BucklerDoran's ShieldDoran's RingDoran's BladeCullVampiric Scepter
5. Gargoyle StoneplateDead Man's PlateZeke's ConvergenceDeath's DanceMortal ReminderLord Dominik's RegardsRapid FirecannonDuskblade of DraktharrRedemptionEdge of NightKnight's VowTrinity ForceZhonya's HourglassLocket of the Iron SolariManamuneRabadon's DeathcapRod of AgesVoid StaffSpirit VisageFrozen HeartPhantom DancerYoumuu's GhostbladeRanduin's OmenIonian Boots of LucidityMorellonomiconMaw of MalmortiusBlade of the Ruined KingSeraph's EmbraceRavenous HydraRunaan's HurricaneMuramanaMercurial ScimitarEssence ReaverArdent CenserThornmailStormrazorGuinsoo's RagebladeArchangel's StaffBanshee's VeilBerserker's GreavesBoots of SwiftnessWit's EndWarmog's ArmorGuardian AngelBlack CleaverMejai's SoulstealerSorcerer's ShoesMercury's TreadsNashor's ToothRylai's Crystal ScepterBloodthirsterSanguine BladeUmbral GlaiveInfinity EdgeTitanic HydraSterak's GageLich BaneAbyssal MaskShard of True IceBulwark of the MountainBlack Mist ScythePauldrons of WhiterockStaff of Flowing WaterMobility BootsForce of NaturePlated SteelcapsChempunk ChainswordChemtech PutrifierCosmic DriveDemonic EmbraceDivine SundererEclipseEverfrostFrostfire GauntletGaleforceGoredrinkerHextech RocketbeltHorizon FocusImmortal ShieldbowImperial MandateKraken SlayerLiandry's AnguishLuden's TempestMikael's BlessingMoonstone RenewerNavori QuickbladesNight HarvesterProwler's ClawRiftmakerSerpent's FangSerylda's GrudgeShurelya's BattlesongStridebreakerSunfire AegisThe CollectorTurbo ChemtankNeedlessly Large RodStopwatchPickaxeB. F. SwordRuby CrystalNull-Magic MantleRejuvenation BeadCloth ArmorLong SwordDaggerAmplifying TomeSapphire CrystalFaerie CharmRejuvenation BeadCloak of AgilityDark SealSteel ShoulderguardsSpectral SickleSpellthief's EdgeRelic ShieldBootsTear of the GoddessSheenBramble VestLost ChapterCaulfield's WarhammerSerrated DirkKircheis ShardAether WispBami's CinderCrystalline BracerForbidden IdolHexdrinkerKindlegemQuicksilver SashSeeker's ArmguardSpectre's CowlOblivion OrbRecurve BowChain VestAegis of the LegionExecutioner's CallingWarden's MailFiendish CodexNegatron CloakPhage Giant's BeltZealTiamatLast WhisperFrostfangTargon's BucklerBlighting JewelGlacial BucklerDoran's ShieldDoran's RingDoran's BladeCullVampiric Scepter
6. Gargoyle StoneplateDead Man's PlateZeke's ConvergenceDeath's DanceMortal ReminderLord Dominik's RegardsRapid FirecannonDuskblade of DraktharrRedemptionEdge of NightKnight's VowTrinity ForceZhonya's HourglassLocket of the Iron SolariManamuneRabadon's DeathcapRod of AgesVoid StaffSpirit VisageFrozen HeartPhantom DancerYoumuu's GhostbladeRanduin's OmenIonian Boots of LucidityMorellonomiconMaw of MalmortiusBlade of the Ruined KingSeraph's EmbraceRavenous HydraRunaan's HurricaneMuramanaMercurial ScimitarEssence ReaverArdent CenserThornmailStormrazorGuinsoo's RagebladeArchangel's StaffBanshee's VeilBerserker's GreavesBoots of SwiftnessWit's EndWarmog's ArmorGuardian AngelBlack CleaverMejai's SoulstealerSorcerer's ShoesMercury's TreadsNashor's ToothRylai's Crystal ScepterBloodthirsterSanguine BladeUmbral GlaiveInfinity EdgeTitanic HydraSterak's GageLich BaneAbyssal MaskShard of True IceBulwark of the MountainBlack Mist ScythePauldrons of WhiterockStaff of Flowing WaterMobility BootsForce of NaturePlated SteelcapsChempunk ChainswordChemtech PutrifierCosmic DriveDemonic EmbraceDivine SundererEclipseEverfrostFrostfire GauntletGaleforceGoredrinkerHextech RocketbeltHorizon FocusImmortal ShieldbowImperial MandateKraken SlayerLiandry's AnguishLuden's TempestMikael's BlessingMoonstone RenewerNavori QuickbladesNight HarvesterProwler's ClawRiftmakerSerpent's FangSerylda's GrudgeShurelya's BattlesongStridebreakerSunfire AegisThe CollectorTurbo ChemtankNeedlessly Large RodStopwatchPickaxeB. F. SwordRuby CrystalNull-Magic MantleRejuvenation BeadCloth ArmorLong SwordDaggerAmplifying TomeSapphire CrystalFaerie CharmRejuvenation BeadCloak of AgilityDark SealSteel ShoulderguardsSpectral SickleSpellthief's EdgeRelic ShieldBootsTear of the GoddessSheenBramble VestLost ChapterCaulfield's WarhammerSerrated DirkKircheis ShardAether WispBami's CinderCrystalline BracerForbidden IdolHexdrinkerKindlegemQuicksilver SashSeeker's ArmguardSpectre's CowlOblivion OrbRecurve BowChain VestAegis of the LegionExecutioner's CallingWarden's MailFiendish CodexNegatron CloakPhage Giant's BeltZealTiamatLast WhisperFrostfangTargon's BucklerBlighting JewelGlacial BucklerDoran's ShieldDoran's RingDoran's BladeCullVampiric Scepter

Vayne Item Build Patch 13.4

Summoner Spells

Starting Items

Trinket

What runes for Vayne S12? The best Vayne runes for are Precision as the Primary and Sorcery as a Secondary. Within the Precision tree, The Best Keystone Rune used will be Fleet Footwork.

Primary

Precision

Fleet Footwork

Triumph

Legend: Alacrity

Coup de Grace

Secondary

Sorcery

Celerity

Gathering Storm

Third

Attack Speed

Adaptive Force

Scaling Health

This section will explain what abilities you level up for this Vayne Build S12. Your first ability for level 1 should be Q Tumble, and then you should start maxing out Q Tumble. After that, you can start leveling up W Silver Bolts followed by E Condemn.

Maxing Skill Order

Q

›

W

›

E