Best Vayne Nexus Blitz Runes
For Vayne, the optimal rune setup is Precision with Lethal Tempo Keystone, yielding a 50.38% win rate, chosen in 97.07% of games, complemented by Resolve as the secondary tree runes.

Precision














Resolve


















Spells
Starting Items
First buy
Best Vayne Nexus Blitz Build
The Trinity Force has a 50.51% win rate and is used in 26.67% of all Vayne games. It is followed by Statikk Shiv and Wit's End as core legendary items for this build.
Best Nexus Blitz Champions
The best champions to play. Analyzed from the highest win rate matches.
Go to Tier List
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Skill Max Order
Priority
- 1st
- 2nd
- 3rd
Ability Order
Leveling path

Q
1
8
10
12
13

W
2
4
5
7
9

E
3
14
15
17
18

R
6
11
16

P
On-Hit Runes

Precision














Domination



















Spells
Starting Items
On-Hit Build
Skill Max Order
- 1st
- 2nd
- 3rd
Ability Order

Q
1
8
10
12
13

W
2
4
5
7
9

E
3
14
15
17
18

R
6
11
16

P