Best Cassiopeia Nexus Blitz Runes

For Cassiopeia, the optimal rune setup is Precision with Conqueror Keystone, yielding a 46.73% win rate, chosen in 78.50% of games, complemented by Sorcery as the secondary tree runes.

Domination
Precision
Keystone-1Keystone-1Keystone-1Keystone-1
Keystone-1Keystone-1Keystone-1
Keystone-1Keystone-1Keystone-1
Keystone-1Keystone-1Keystone-1
Domination
Sorcery
Keystone-1Keystone-1Keystone-1
Keystone-1Keystone-1Keystone-1
Keystone-1Keystone-1Keystone-1
OffenseOffenseOffense
FlexFlexFlex
DefenseDefenseDefense

Spells

Flash Ghost

Starting Items

First buy

Doran's RingHealth PotionStealth Ward

Best Cassiopeia Nexus Blitz Build

The Liandry's Anguish has a 42.00% win rate and is used in 28.00% of all Cassiopeia games. It is followed by Archangel's Staff and Void Staff as core legendary items for this build.

  1. 1st
    Liandry's Anguish
    →
  2. 2nd
    Archangel's Staff
    →
    ⇅ Rylai's Crystal Scepter Rabadon's Deathcap
  3. 3rd
    Void Staff
    →
    ⇅ Zhonya's Hourglass Morellonomicon
  4. 4th
    Demonic Embrace
    →
    ⇅ Deathfire Grasp Cosmic Drive
  5. 5th
    Shadowflame
Best Nexus Blitz Champions
The best champions to play. Analyzed from the highest win rate matches.
Go to Tier List
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Skill Max Order

Priority

  1. E
    Twin Fang
    →
    1st
  2. Q
    Noxious Blast
    →
    2nd
  3. W
    Miasma
    3rd

Ability Order

Leveling path

Noxious Blast
Q
2
8
10
12
13
Miasma
W
3
14
15
17
18
Twin Fang
E
1
4
5
7
9
Petrifying Gaze
R
6
11
16
Serpentine Grace
P