Cassiopeia Item Build
Every point of ability power Cassiopeia buys both ramps her poison and keeps her afloat, since Twin Fang heals her for a cut of the damage it deals and refunds mana on a kill. The payoff on the Abyss is a mage who sustains herself through the grind she creates, with no trip back to the fountain to lean on instead.
Best Cassiopeia Runes
Conqueror lines up with the poke war Cassiopeia thrives in on the Abyss, chipping the grouped enemies with Noxious Blast and holding Petrifying Gaze to stun the pile if they face her. Every fight is a packed 5v5, so build around the mana and damage that keep her poison flowing across the bridge.
Precision
Primary
ConquerorGain stacks of adaptive force when attacking enemy champions. After reaching 12 stacks, heal for a portion of damage you deal to champions.
91% · 41.3%65% · 46.7%45% · 48.4%
Keystone plus three minors from Precision, two from Sorcery, then three shards — no runebook, no masteries.
Sorcery
Secondary
52% · 41.7%48% · 42.4%
Cassiopeia Skill Order
Ranks at 4, 5, 7 and 9 all feed Twin Fang, the follow-up hit that converts standing poison into damage and returns a slice of it as health. Noxious Blast holds a single rank until 8, so early chip leans on the poison already applied rather than on its own scaling.
Cassiopeia ARAM Abilities
Look past the poison for a second and Twin Fang is also her sustain button, healing a cut of every hit and refunding mana whenever it lands the kill. Petrifying Gaze rewards positioning too, a hard stun on anyone facing her and only a slow on the backs turned to run.








































