Twitch Item Build
Attack speed is secretly Twitch's poison-application rate: the faster he fires, the quicker Deadly Venom stacks pile onto a stationary front-to-back line, and the more true damage is already ticking before Contaminate ever detonates it. Crit turns each piercing bolt into a real hit rather than a tickle. He buys zero defense, trusting the frontline and the endless fight to hand him his scaling window.
Best Twitch Runes
Lethal Tempo matches how Twitch fights on the Abyss, since every second his poison stacks tick on the grouped team feeds a bigger Contaminate. The bridge gives the enemy nowhere to spread, so the page backs the positioning that lets him line up Spray and Pray down the whole clump. Ambush hands him the stealth to reach a flank before he opens fire.
Precision
Primary
Lethal TempoAttacking an enemy champion grants you Attack Speed, up to 6 stacks. At max stacks, deal bonus adaptive damage On-Attack.
68% · 46.2%92% · 46.0%71% · 46.7%
Keystone plus three minors from Precision, two from Domination, then three shards — no runebook, no masteries.
Domination
Secondary
78% · 47.0%71% · 46.7%
Twitch Skill Order
Taking 5 percent less damage on the Abyss is the small cushion that lets Twitch commit to Contaminate early, and it takes 4, 5, 7 and 9 so the poison detonation grows before anything else. Ambush picks up 8 through 13, Venom Cask holds until 14.
Twitch ARAM Abilities
Venom Cask is the tool that is not just stealth, a lobbed pot that slows a group and paints them all with poison from range. Contaminate then pays that off, blasting every enemy his venom is already stuck to. Ambush even refreshes the moment a poisoned champion dies.











































