Mewtwo's 154 Special and 130 Speed have no real answer in Gen 1. S-Tier and Yellow's endgame prize deep in Cerulean Cave.
744HP106Attack110Defense90Speed130Sp.Def154Sp.Atk154
Weak to
Special
Sweeper
130Speed · Extreme

Is Mewtwo Good in Yellow Playthrough?

Cerulean Cave after beating the Champion. Mewtwo is the strongest Pokemon in Gen 1 by a wide margin, but there's nothing left to use it on in the story by the time you catch it. A postgame trophy with numbers that would have trivialized everything.

StrongGoodEvenToughBadSGGSSESSSSSSGBrockGym 1MistyGym 2SurgeGym 3ErikaGym 4KogaGym 5SabrinaGym 6BlaineGym 7GiovanniGym 8LoreleiE4BrunoE4AgathaE4LanceE4BlueChamp*MewtwoCatchable
Brock
Gym 1
Strong

Mewtwo resists most of Brock's coverage and hits back hard.

Easy KO
Geodude
Lv 10
RockGround
Rock Head
Tackle
Easy KO
Onix
Lv 12
RockGround
Rock Head
TackleScreechBindBide
Misty
Gym 2
Good

Mewtwo has the type edge here and should clean up Misty's team.

Easy KO
Staryu
Lv 18
Water
Illuminate
TackleWater Gun
Even
Starmie
Lv 21
WaterPsychic
Illuminate
TackleWater GunHardenBubble Beam
Lt. Surge
Gym 3
Good

Mewtwo has the type edge here and should clean up Lt. Surge's team.

You Win
Raichu
Lv 28
Electric
Static
ThunderboltMega PunchMega KickGrowl
Erika
Gym 4
Strong

Mewtwo resists most of Erika's coverage and hits back hard.

Easy KO
Tangela
Lv 30
Grass
Chlorophyll
ConstrictBindMega DrainVine Whip
Easy KO
Weepinbell
Lv 32
GrassPoison
Chlorophyll
Razor LeafSleep PowderStun SporeAcid
Easy KO
Gloom
Lv 32
GrassPoison
Chlorophyll
Petal DanceStun SporeSleep PowderAcid
Koga
Gym 5
Strong

Mewtwo resists most of Koga's coverage and hits back hard.

Easy KO
Venonat
Lv 44
BugPoison
Compound Eyes
ToxicTackleSleep PowderPsychic
Easy KO
Venonat
Lv 46
BugPoison
Compound Eyes
ToxicPsybeamSupersonicPsychic
Easy KO
Venonat
Lv 48
BugPoison
Compound Eyes
ToxicDouble EdgeSleep PowderPsychic
Easy KO
Venomoth
Lv 50
BugPoison
Shield Dust
Leech LifeDouble TeamPsychicToxic
Sabrina
Gym 6
Even

Mewtwo trades roughly evenly with Sabrina's team.

You Win
Abra
Lv 50
Psychic
Synchronize
Flash
Even
Kadabra
Lv 50
Psychic
Synchronize
KinesisRecoverPsychicPsywave
Even
Alakazam
Lv 50
Psychic
Synchronize
PsywaveRecoverPsychicReflect
Blaine
Gym 7
Strong

Mewtwo resists most of Blaine's coverage and hits back hard.

Easy KO
Ninetales
Lv 48
Fire
Flash Fire
FlamethrowerTail WhipQuick AttackConfuse Ray
Easy KO
Rapidash
Lv 50
Fire
Run Away
StompGrowlFire SpinTake Down
Easy KO
Arcanine
Lv 54
Fire
Intimidate
FlamethrowerFire BlastReflectTake Down
Giovanni
Gym 8
Strong

Mewtwo resists most of Giovanni's coverage and hits back hard.

Easy KO
Dugtrio
Lv 50
Ground
Sand Veil
DigSand AttackFissureEarthquake
Easy KO
Persian
Lv 53
Normal
Limber
ScreechDouble TeamFury SwipesSlash
Easy KO
Nidoqueen
Lv 53
PoisonGround
Poison Point
EarthquakeTail WhipThunderDouble Kick
Easy KO
Nidoking
Lv 55
PoisonGround
Poison Point
EarthquakeLeerThunderDouble Kick
Easy KO
Rhydon
Lv 55
GroundRock
Lightning Rod
Rock SlideFury AttackHorn DrillEarthquake
Lorelei
Elite Four
Strong

Mewtwo resists most of Lorelei's coverage and hits back hard.

Easy KO
Dewgong
Lv 54
WaterIce
Thick Fat
Bubble BeamAurora BeamRestTake Down
Easy KO
Cloyster
Lv 53
WaterIce
Shell Armor
SupersonicClampIce BeamSpike Cannon
You Win
Slowbro
Lv 54
WaterPsychic
Oblivious
PsychicSurfWithdrawAmnesia
You Win
Jynx
Lv 56
IcePsychic
Oblivious
Double SlapIce PunchLovely KissThrash
Easy KO
Lapras
Lv 56
WaterIce
Water Absorb
Body SlamConfuse RayBlizzardHydro Pump
Bruno
Elite Four
Strong

Mewtwo resists most of Bruno's coverage and hits back hard.

Easy KO
Onix
Lv 53
RockGround
Rock Head
Rock SlideScreechSlamDig
Easy KO
Hitmonchan
Lv 55
Fighting
Keen Eye
Ice PunchThunder PunchFire PunchDouble Team
Easy KO
Hitmonlee
Lv 55
Fighting
Limber
Double KickMega KickHigh Jump KickDouble Team
Easy KO
Onix
Lv 56
RockGround
Rock Head
Rock SlideScreechSlamEarthquake
Easy KO
Machamp
Lv 58
Fighting
Guts
LeerKarate ChopStrengthSubmission
Agatha
Elite Four
Strong

Mewtwo resists most of Agatha's coverage and hits back hard.

Easy KO
Gengar
Lv 56
GhostPoison
Cursed Body
Confuse RaySubstituteLickMega Drain
Easy KO
Golbat
Lv 56
PoisonFlying
Inner Focus
SupersonicToxicWing AttackLeech Life
Easy KO
Haunter
Lv 55
GhostPoison
Levitate
Confuse RayLickHypnosisDream Eater
Easy KO
Arbok
Lv 58
Poison
Intimidate
WrapGlareScreechAcid
Easy KO
Gengar
Lv 60
GhostPoison
Cursed Body
Confuse RayPsychicHypnosisDream Eater
Lance
Elite Four
Strong

Mewtwo resists most of Lance's coverage and hits back hard.

Easy KO
Gyarados
Lv 58
WaterFlying
Intimidate
Dragon RageLeerHydro PumpHyper Beam
Easy KO
Dragonair
Lv 56
Dragon
Shed Skin
Thunder WaveSlamThunderboltHyper Beam
Easy KO
Dragonair
Lv 56
Dragon
Shed Skin
Bubble BeamWrapIce BeamHyper Beam
Easy KO
Aerodactyl
Lv 60
RockFlying
Rock Head
Wing AttackSwiftFlyHyper Beam
Easy KO
Dragonite
Lv 62
DragonFlying
Inner Focus
BlizzardFire BlastThunderHyper Beam
Blue
Champion
Good

Mewtwo has the type edge here and should clean up Blue's team.

Easy KO
Sandslash
Lv 61
Ground
Sand Veil
SlashPoison StingEarthquakeFury Swipes
Even
Alakazam
Lv 59
Psychic
Synchronize
PsybeamRecoverPsychicKinesis
You Win
Exeggutor
Lv 61
GrassPsychic
Chlorophyll
BarrageHypnosisStompLeech Seed
Easy KO
Ninetales
Lv 61
Fire
Flash Fire
Confuse RayTail WhipQuick AttackFire Spin
You Win
Magneton
Lv 63
Electric
Magnet Pull
ThunderboltThunder WaveSwiftScreech
Easy KO
Vaporeon
Lv 65
Water
Water Absorb
Aurora BeamMistQuick AttackHydro Pump

Catchable

Post-game only
Type
Psychic
Tier
S

Catch Mewtwo in Cerulean Cave (interact, Lv 70, limited). Defeat Elite Four. Cerulean Cave opens after entering the Hall of Fame. Navigate to B1F where Mewtwo waits at Level 70.

View Mewtwo locations

How to Get Mewtwo in Yellow

Mewtwo broods at the back of Cerulean Cave, sealed away until you've beaten the Elite Four. At level 70 with a catch rate of 3 it's the hardest catch in the game, and the cave holds exactly one.

1 location to catch Mewtwo

Badge 8
Post-Game

Mewtwo Weakness

Type-wise, Mewtwo takes extra damage from Bug. Ghost moves do nothing thanks to a full immunity. Mewtwo's special bulk (base 154 Special) helps absorb special-type weaknesses, though physical moves exploit the lower Defense.

Mewtwo Weakness and Resistance Chart
DamageTypes
2x (Weak)Bug
0.5x (Resist)Fighting, Psychic
0x (Immune)Ghost
Gen I Type Chart
  • Only 15 types exist — Dark, Steel, and Fairy are absent
  • Ghost has no effect on Psychic (a known bug, fixed in Gen II)
  • Special stat governs both offense and defense — no Sp.Atk / Sp.Def split

What is Mewtwo Weak Against

Good
1Weak
2Resist
1Immune
Score+3
4xCritical
None
2xWeak
¼xResist
None
0xImmune

What is Mewtwo Strong Against

2Strong
1Resisted
0Immune
Score+1
½xResisted
0xImmune
None

Best Pokemon Against Mewtwo

Parasect
Parasect
BugGrass
C
Venomoth
Venomoth
BugPoison
C

Mewtwo Evolutions

No breeding, no evolution. Mewtwo is a Psychic legendary with 744 base stat total that you obtain once and build around. View every chain in the Evolution Chart.

How to Evolve

No Evolution
Mewtwo
#150Mewtwo
Does not evolve
Breeding not available · Introduced in Gen 2

Y Mewtwo Best Moveset

The strongest Pokemon available by every measure. 154 Special fires MovePsychic from a type with no viable resistance, 130 Speed outspeeds everything non-Electrode, and MoveRecover keeps it healthy indefinitely. MoveBlizzard and MoveThunderbolt cover the rare neutral targets. Nothing in the format approaches this level of dominance.

Best Build

Experimental
Utility
Ability
Unknown
Item
None
Best Nature for Mewtwo
HardyNEUTRAL

Utility Moveset

  • AmnesiaUtility
  • PsychicSTAB
  • RecoverRecovery
  • Ice Beam

Moves List

TMs define Mewtwo's movepool. The natural moves cover basics with Psychic and Confusion, but the real versatility comes from technical machines giving it coverage across 7 types. That's where the options open up.

Level-Up Moves

Lv 1
Confusion
—7510025Psychic
Lv 1
Disable
D—5520Normal
Lv 1
Psychic
B13510010Psychic
Lv 1
Swift
C60—20Normal
Lv 63
Barrier
D——30Psychic
Lv 66
Psychic
B13510010Psychic
Lv 70
Recover
B——20Normal
Lv 75
Mist
———30Ice
Lv 81
Amnesia
B——20Psychic

TM Moves

All 35 TMs are obtainable before the Elite Four

TM
TM34D——10Normal
TM14
BlizzardPokémon Mansionbadge 6
A110905Ice
TM08
Body SlamS.S. Annebadge 2
C8510015Normal
TM11C6510020Water
TM18
Counter-5Celadon Department Storebadge 3
D—10020Fighting
TM32
Double TeamSafari Zonebadge 3
———15Normal
TM10
Double-EdgeRocket Hideoutbadge 3
B12010015Normal
TM38B120855Fire
HM05D—7020Normal
TM15
Hyper BeamRocket Game Cornerbadge 3
B150905Normal
TM13A9510010Ice
TM05
Mega KickCeladon Department Storebadge 3
C120755Normal
TM01
Mega PunchMt. Moonbadge 1
C808520Normal
TM35
MetronomePokémon Labbadge 6
D——10Normal
TM31
MimicSaffron Citybadge 5
D——10Normal
TM29
PsychicSaffron Citybadge 5
B13510010Psychic
TM46——10015Psychic
TM20
RageRoute 15badge 3
D2010020Normal
TM33
ReflectKanto Power Plantbadge 3
C——20Psychic
TM44
RestS.S. Annebadge 2
C——10Psychic
TM19
Seismic TossRoute 25badge 1
D—10020Fighting
TM36
Self-DestructSilph Co.badge 5
B2001005Normal
TM40
Skull BashSafari Zonebadge 4
B10010010Normal
TM22
Solar BeamPokémon Mansionbadge 6
B12010010Grass
HM04
StrengthFuchsia Citybadge 4
—8010015Normal
TM17
SubmissionCeladon Department Storebadge 3
C808025Fighting
TM50
SubstituteRocket Game Cornerbadge 3
C——10Normal
TM09
Take DownSilph Co.badge 3
C908520Normal
TM30
Teleport-6Route 9badge 2
———20Psychic
TM25
ThunderKanto Power Plantbadge 5
C1107010Electric
TM45
Thunder WaveRoute 24badge 1
C—10020Electric
TM24A9510015Electric
TM06C—9010Poison
TM49B8010010Normal
TM12
Water GunMt. Moonbadge 1
C4010025Water

Tutor Moves

Mewtwo can't learn any Tutor moves

Base Stats

Base Stats
Legend
HP106
B
Attack110
B
Defense90
B
Sp. Atk154
S
Sp. Def154
S
Speed130
A
Total744
Details
Catch Rate
Legendary3 / 255
Growth Rate
Slow1.25M XP
Height2.0 m
Weight122.0 kg
Base XP340
EV Yield
HPAtkDefSpA+3SpDSpe
Strong Special Attack training target
Pokedex Entry

Its DNA is almost the same as MEW’s. However, its size and disposition are vastly different.

Pokemon Yellow

Mewtwo Yellow Guide

  • Mega Evolution isn't available in Yellow, but Mewtwo does have a Mega form in Gen 6-7 games (X/Y, ORAS, Sun/Moon). Mega Mewtwo hits 844 BST.

  • Mewtwo is a static encounter at Cerulean Cave in Yellow. Mewtwo appears at level 70. Prerequisite: Defeat Elite Four. Save before the encounter. These one-shot Pokemon don't respawn if you knock them out or run out of Poke Balls.

  • Yes. Mewtwo is not available during the main story. It can only be obtained after entering the Hall of Fame. Mewtwo becomes available after the main story is complete in Yellow.

  • In Yellow, Mewtwo plays as a sweeper. It outspeeds most threats, so it can pressure opponents before they move. Psychic is the primary attack.

Game Availability

Mewtwo has appeared in 21 games since Red & Blue, spanning 9 generations. As a Legendary, it's typically a one-per-save encounter tied to the story or post-game content.

Explore

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