Diablo 4 Poison Damage

The Diablo 4 Poison Damage Stat Explained, what the Poison Damage Stat does. We also list every Aspect, Unique Armor and Weapon, Skill, Paragon that affects the Poison Damage Stat.

How does Poison Damage work in D4

You can filter every Paragon, Skill, Aspect, Unique and Passive by Class using the dropdowns below. Keep in mind the filter will limit what you see if used, so only use if you want to view what affects that specific class

Poison Damage Effect
Stat	Effect
Poison Damage	Increases Poison Damage
Equipment that can have Poison Damage	Chest Armor Chest Armor Ring

Best Builds To Use with Poison Damage Stat

We have a total of (5) builds that make use of the Poison Damage Stat. You can click/tap any Poison Damage build below to view the complete Build.

Poison Imbuement Build

Rogue

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Barrage Build

Rogue

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Best Builds

Best Unique Weapons and Armor That have Poison Damage

The best unique equipment to use with the Poison Damage stat in D4 is Mad Wolf's Glee, which is a Unique Chest Armor.

Mad Wolf's Glee

Druid • Unique Chest Armor

Strong Synergy

Physical Damage
Poison Damage
Damage Reduction from Poisoned Enemies
Movement Speed

Werewolf form is now your true form, and you gain +3 Ranks to all Werewolf Skills.

All Stats
Attack Speed
Life Steal
Poison Resistance

Lucky Hit: Up to a [10 - 20%] chance to trigger a Poison nova that applies [X] Poisoning damage over 5 seconds to enemies in the area.

Overpower Damage

Damage while Shapeshifted
Damage to Poisoned Enemies
Damage while Healthy
Ranks to All Skills

Debilitating Roar and Blood Howl deal [X] damage to Nearby Poisoned enemies.

Damage While Shapeshifted
Poison Resistance
Maximum Spirit
Life On Kill

Lucky Hit: Storm Skills have up to a [15 - 25%] chance to grant 10 Spirit. Your base Storm Skills are now also Werewolf Skills.

Lightning Resistance
Poison Resistance

Damage while Shapeshifted
Critical Strike Damage While in Werewolf Form
Overpower Damage While in Werebear Form
Ranks to Quickshift

Gain a bonus when you kill with Shapeshifting Skill: Werewolf: Your next Non-Ultimate Werebear Skill costs no Resource and has no Cooldown. Werebear: Your next Werewolf Skill will Heal you for [X] when damage is first dealt.

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Best Uniques

Best Aspects To Use with Poison Damage

The best aspects to use with the Poison Damage Stat in D4 is Aspect of Noxious Ice, which is a Utility Aspect and can only be used on Helm, Chest, Gloves, Boots, Shield, Amulet (+50%) Equipment Slots.

Aspect of Noxious Ice

Rogue • Utility

Strong Synergy

Chilled enemies Poisoned by Poison Imbuement will be further Chilled for 20% per second. You deal [14-29%] additional Poison damage to Frozen enemies.

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Aspect of Bursting Venoms

Rogue • Offensive

Average Synergy

Lucky Hit: Critical Strikes with Poison Imbued Skills have up to a 10% chance to create a toxic pool that deals [X] Poisoning damage over 3 seconds to enemies within. While standing in the pool, Poison Imbuement has no Cooldown and no Charge limit.

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Aspect of the Blurred Beast

Druid • Offensive

Average Synergy

While dashing, Shred seeks out Neaby Poisoned enemies instantly dealing [70-100%] of the Poisoning damage to them.

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Aspect of the Dark Howl

Druid • Utility

Average Synergy

Debilitating Roar is now a Werewolf Skill. In addition, Debilitating Roar will Immobilze Poisoned enemies for [2-4] seconds.

Poison Trap no longer breaks Stealth and triggers no Cooldown or arm time while you are in Stealth. All Poision Traps activate when you exit Stealth and Poison Trap's Cooldown will be [5-8] seconds per trap placed.

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Aspect of the Changeling's Debt

Druid • Resource

Codex

Average Synergy

Damaging a Poisoned enemy with a Werebear Skill will instantly deal [120-150%] of the Poisoning damage and consume the Poisoning.

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Toxic Alchemist's Aspect

Rogue • Offensive

Average Synergy

Lucky Hit: Damaging a Poisoned enemy with a Shadow Imbued Skill has up to a 75% chance to create a toxic explosion that applies [.11-.16] Poisoning damage over 5 seconds to the target and surrounding enemies.

Poison Creeper’s active also casts Landslide in a circle around you. Earth Skills deal [10 - 20%] increased damage to Poisoned enemies.

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Pestilent Points Aspect

Rogue • Offensive

New

Average Synergy

Every third cast of Puncture is Poison Imbued with [100 - 150%] of normal potency.

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Best Aspects

Best Paragons To Use with Poison Damage

The best paragon to use with the Poison Damage stat in D4 is Bane (Druid), which is a Rare Glyph Node.

Constricting Tendrils

Druid • Legendary Board

Average Synergy

Lucky Hit: Nature Magic Skills have up to a 15% chance to entangle the enemy with vines, Immobilizing them for 2 seconds and Poisoning them for 120% of the Base damage dealt over 4 seconds.

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Heightened Malice

Druid • Legendary Board

Average Synergy

While there are 3 or more Poisoned enemies Nearby, you deal 45% increased damage.

Description:
For every 5 Intelligence purchased within range, you deal +2 - 10% (0.4% Per Level) increased Poison damage.
Radius Bonus:
Poisoning damage effects have a 10% chance to deal double the amount of damage over their duration.
Radius Requirement:

25 Intelligence

Description:
For every 5 Strength purchased within range, you deal +2 - 10% (0.4% Per Level) increased Poison damage.
Radius Bonus:
Poisoning damage effects have a 10% chance to deal double the amount of damage over their duration.
Radius Requirement:

25 Strength

Description:
For every 5 Dexterity purchased within range, you deal +2 - 10% (0.4% Per Level) increased damage to Poisoned targets.
Radius Bonus:
Poisoning damage effects last x33.3% longer.
Radius Requirement:

25 Dexterity

Description:
For every 5 Intelligence purchased within range, you deal +2 - 10% (0.4% Per Level) increased damage to Poisoned targets.
Radius Bonus:
Poisoning damage effects last x33.3% longer.
Radius Requirement:

25 Intelligence