Diablo 4 Alchemical Advantage

The Diablo 4 Alchemical Advantage is a Imbuements Rogue Passive. Using the Alchemical Advantage You gain + {1% / 2% / 3%} increased Attack Speed for each enemy you've Poisoned, up to +15%.

B Tier

Imbuements

Best Builds To Use with Alchemical Advantage

We have a total of (5) builds that use the Rogue Alchemical Advantage Passive. You can click/tap any Alchemical Advantage build below to view the complete Build.

Imbuement Build

Rogue

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Poison Imbuement Build

Rogue

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Penetrating Shot Build

Rogue

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Best Rogue Builds

Best Unique Weapons and Armor To Use with Alchemical Advantage

The best unique equipment to use with Alchemical Advantage skill in D4 is Asheara's Khanjar, which is a Unique Dagger.

Asheara's Khanjar

Rogue • Unique Dagger

Average Synergy

Damage to Close Enemies

Basic Skill Damage
Damage to Crowd Controlled Enemies
Damage for X seconds on Elite Kill
Lucky Hit Chance

Hits with this weapon increase your Attack Speed by [4 - 6%] for 4 seconds, up to [20 - 30%] .

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Best Rogue Uniques

Best Aspects To Use with Alchemical Advantage

The best aspects to use with Alchemical Advantage passive in D4 is Accelerating Aspect, which is a Offensive Aspect and can only be used on Gloves, Offhand, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%) Equipment Slots.

Accelerating Aspect

All • Offensive

Average Synergy

Critical Strikes with Core Skills increase your Attack Speed by [15-25%] for 3 seconds.

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Aspect of Bursting Venoms

Rogue • Offensive

Average Synergy

Lucky Hit: Critical Strikes with Poison Imbued Skills have up to a 10% chance to create a toxic pool that deals [X] Poisoning damage over 3 seconds to enemies within. While standing in the pool, Poison Imbuement has no Cooldown and no Charge limit.

Basic Skills gain [15-30%] Attack Speed.

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Aspect of Noxious Ice

Rogue • Utility

Average Synergy

Chilled enemies Poisoned by Poison Imbuement will be further Chilled for 20% per second. You deal [14-29%] additional Poison damage to Frozen enemies.

Poison Trap no longer breaks Stealth and triggers no Cooldown or arm time while you are in Stealth. All Poision Traps activate when you exit Stealth and Poison Trap's Cooldown will be [5-8] seconds per trap placed.

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Toxic Alchemist's Aspect

Rogue • Offensive

Average Synergy

Lucky Hit: Damaging a Poisoned enemy with a Shadow Imbued Skill has up to a 75% chance to create a toxic explosion that applies [.11-.16] Poisoning damage over 5 seconds to the target and surrounding enemies.

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Pestilent Points Aspect

Rogue • Offensive

New

Average Synergy

Every third cast of Puncture is Poison Imbued with [100 - 150%] of normal potency.

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Best Rogue Aspects

Best Paragons To Use with Alchemical Advantage

The best paragon to use with Alchemical Advantage skill in D4 is Bane (Rogue), which is a Rare Glyph Node.

Bane (Rogue)

Rogue • Rare Glyph

Good Synergy

Description:
For every 5 Strength purchased within range, you deal +2 - 10% (0.4% Per Level) increased Poison damage.
Radius Bonus:
Poisoning damage effects have a 10% chance to deal double the amount of damage over their duration.
Radius Requirement:

25 Strength

Description:
For every 5 Intelligence purchased within range, you deal +2 - 10% (0.4% Per Level) increased damage to Poisoned targets.
Radius Bonus:
Poisoning damage effects last x33.3% longer.
Radius Requirement:

25 Intelligence

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Best Rogue Paragons

Best Skills To Use with Alchemical Advantage

The best skill synergy with the Alchemical Advantage passive in D4 is Poison Imbuement, and there is also a strong passive synergy with Debilitating Toxins.

Poison Trap

Rogue •

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