Diablo 4 Poison Imbuement

The Diablo 4 Poison Imbuement is a Poison Damage Imbuements Rogue Skill with a lucky hit chance of 33%. You can upgrade to Enhanced Poison Imbuement, and then the last upgrade you will choose between Blended Poison Imbuement or Mixed Poison Imbuement.

Poison Imbuement Stats and Upgrades

Poison Imbuement

Rogue •

Imbuements Active

Poison

Lucky Hit Chance: 33%

Cooldown: 13

Imbue your weapons with lethal poison. Your next 2 Imbueable Skills deal Poison damage and apply {100% / 110% / 120% / 130% / 140%} of their Base damage as additional Poisoning damage over 5 seconds.

Enhanced

Poison Imbuement's Poisoning Duration is increased by 1 second.

Blended

Critical Strikes with Poison Imbued Skills deal 75% increased Poisoning damage.

Mixed

Lucky Hit: Poison Imbued Skills have up to a 30% chance to apply double the amount of Poisoning damage over time.

Best Builds To Use with Poison Imbuement

We have a total of (6) builds that use the Rogue Poison Imbuement Skill. You can view the best Poison Imbuement builds below and the complete guide by Clicking/Tapping them.

Poison Imbuement Build

Rogue

Shadow Imbuement Build

Rogue

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Flurry Build

Rogue

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Best Rogue Builds

Best Unique Weapons and Armor To Use with Poison Imbuement

The best unique equipment to use with Poison Imbuement skill in D4 is Andariel's Visage, which is a Unique Helm.

Andariel's Visage

All • Unique Helm

Average Synergy

All Stats
Attack Speed
Life Steal
Poison Resistance

Lucky Hit: Up to a [10 - 20%] chance to trigger a Poison nova that applies [X] Poisoning damage over 5 seconds to enemies in the area.

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Best Rogue Uniques

Best Aspects To Use with Poison Imbuement

The best aspects to use with Poison Imbuement skill in D4 is Aspect of Noxious Ice, which is a Utility Aspect and can only be used on Helm, Chest, Gloves, Boots, Shield, Amulet (+50%) Equipment Slots.

Aspect of Noxious Ice

Rogue • Utility

Strong Synergy

Chilled enemies Poisoned by Poison Imbuement will be further Chilled for 20% per second. You deal [14-29%] additional Poison damage to Frozen enemies.

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Aspect of Bursting Venoms

Rogue • Offensive

Good Synergy

Lucky Hit: Critical Strikes with Poison Imbued Skills have up to a 10% chance to create a toxic pool that deals [X] Poisoning damage over 3 seconds to enemies within. While standing in the pool, Poison Imbuement has no Cooldown and no Charge limit.

Poison Trap no longer breaks Stealth and triggers no Cooldown or arm time while you are in Stealth. All Poision Traps activate when you exit Stealth and Poison Trap's Cooldown will be [5-8] seconds per trap placed.

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Toxic Alchemist's Aspect

Rogue • Offensive

Average Synergy

Lucky Hit: Damaging a Poisoned enemy with a Shadow Imbued Skill has up to a 75% chance to create a toxic explosion that applies [.11-.16] Poisoning damage over 5 seconds to the target and surrounding enemies.

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Pestilent Points Aspect

Rogue • Offensive

New

Average Synergy

Every third cast of Puncture is Poison Imbued with [100 - 150%] of normal potency.

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Best Rogue Aspects

Best Paragons To Use with Poison Imbuement

The best paragon to use with Poison Imbuement skill in D4 is Bane (Rogue), which is a Rare Glyph Node.

Bane (Rogue)

Rogue • Rare Glyph

Strong Synergy

Description:
For every 5 Strength purchased within range, you deal +2 - 10% (0.4% Per Level) increased Poison damage.
Radius Bonus:
Poisoning damage effects have a 10% chance to deal double the amount of damage over their duration.
Radius Requirement:

25 Strength

Description:
For every 5 Intelligence purchased within range, you deal +2 - 10% (0.4% Per Level) increased damage to Poisoned targets.
Radius Bonus:
Poisoning damage effects last x33.3% longer.
Radius Requirement:

25 Intelligence

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Best Rogue Paragons

Best Skills and Passives To Use with Poison Imbuement

The best skills to use with the Poison Imbuement skill in D4 is Poison Trap, and there is also a strong passive synergy with Debilitating Toxins.

Poison Trap

Rogue •

Subterfuge Active