Karthus Counter Pick
The Best Karthus Counter Picks in League of Legends for patch 13.4, Ranked Boost recommends these picks due to their win condition and abilities.
Karthus is Weak Against
Statistically, these counter picks have a Higher Win Rate in patch 13.4. The strongest counter would be Katarina, a to play champion who currently has a Win Rate of (Average) and Play Rate of (High).